News

December 6, 2021

Scilex Holding Company, a Sorrento Therapeutics Inc. Subsidiary, and Vickers Vantage Corp I (NASDAQ: VCKA) (“SPAC”) Enter into Letter of Intent for Proposed Business Combination

Scilex Holding Company (Scilex) a subsidiary of Sorrento Therapeutics, Inc. (Nasdaq: SRNE), and Vickers Vantage Corp I (Nasdaq: VCKA) announce signing of a letter of intent for a proposed business combination, which provides for a pre-transaction equity value of Scilex of approximately $1.5 billion, subject to adjustment, with expected gross proceeds of up to $140 million. Proposed business combination would create a publicly traded […] Read More »

August 19, 2021

Scilex Holding Company, a Sorrento Therapeutics, Inc. Subsidiary Announces Expansion of Ztlido® Managed Care Coverage for Additional 33 Million Lives

PALO ALTO, Calif., Aug. 19, 2021 (GLOBE NEWSWIRE) — Scilex Holding Company (SCILEX), a subsidiary of Sorrento Therapeutics, Inc. (NASDAQ: SRNE), announced that, effective September 1, 2021, ZTlido® (lidocaine topical system) 1.8% has been added to multiple formularies, including two national PBMs (Pharmacy Benefit Managers), a national health plan and two regional health plans – thereby expanding coverage by up to 33 […] Read More »

July 20, 2021

Scilex Holding Company, a Sorrento Company, Announces Complete Enrollment on Non-Opioid Injectable SP-102 (SEMDEXA™) Phase 3 Pivotal Trial C.L.E.A.R. Program For Sciatica Pain Management

PALO ALTO, Calif., July 20, 2021 (GLOBE NEWSWIRE) -- Scilex Holding Company (“Scilex”), a wholly-owned subsidiary of Sorrento Therapeutics, Inc. (Nasdaq: SRNE, “Sorrento”), today announced complete enrollment of SP-102 (SEMDEXA™) Phase 3 Pivotal Trial C.L.E.A.R. Program, a corticosteroid injectable dexamethasone sodium phosphate gel for the treatment of lumbosacral radicular pain, or sciatica. SP-102 has received Fast Track status from the FDA. Read More »

April 9, 2021

Scilex Holding, A Subsidiary of Sorrento, Has Received From FDA a sNDA Approval for Ztlido® Label Expansion

Palo Alto, California, April 9, 2021 — Scilex Holding (“Scilex”), an over 99% owned subsidiary of Sorrento Therapeutics (NASDAQ: SRNE, “Sorrento”), has received a supplemental new drug application (sNDA) approval from the FDA for ZTlido® to make efficacy labeling change with clinical data. ZTlido® is the only lidocaine topical system that has been studied under […] Read More »

March 1, 2021

Sorrento Therapeutics and Scilex Holding, a Majority Owned Subsidiary, Have Entered Into an Exclusive Licensing Term Sheet With Aardvark Therapeutics to Acquire Its ARD-301 For the Treatment of Chronic Pain, Fibromyalgia, and Chronic Long Haul Covid Syndrome

SAN DIEGO, Calif., March 01, 2021 (GLOBE NEWSWIRE) — Sorrento Therapeutics (NASDAQ: SRNE, “Sorrento”) and Scilex Holdings Company (“Scilex”), a majority owned subsidiary of Sorrento, have entered into an exclusive licensing term sheet with Aardvark Therapeutics (“Aardvark”) to acquire Aardvark’s proprietary formulation, Delayed Burst Release Low Dose Naltrexone (DBR-LDN), or ARD-301, for the treatment of […] Read More »

October 9, 2020

Sorrento COVID-19 R&D October 13, 2020 Pipeline Call Details Released

SAN DIEGO, Oct. 09, 2020 (GLOBE NEWSWIRE) — Sorrento Therapeutics, Inc. (Nasdaq: SRNE, “Sorrento”) today released details about its upcoming COVID-19 Pipeline Update call and webcast on October 13th, 2020. Title: Sorrento Therapeutics COVID-19 Pipeline Update, R&D Discussion and Management Q&A Conference ID: 2066037 Date of call: 10/13/2020 Time of call: 16:30 Eastern Time Expected Duration: 60 minutes + questions (analysts and general public) […] Read More »

October 7, 2020

Scilex Holding Company, a Subsidiary of Sorrento Therapeutics, Announces Continuous Sales Growth in ZTlido® and Expects to Complete Enrollment on its SP-102 (SEMDEXA™) Phase 3 Pivotal Trial Program in 2020

PALO ALTO, Calif., Oct. 07, 2020 (GLOBE NEWSWIRE) — Scilex Holding Company (“Scilex”), a majority-owned subsidiary of Sorrento Therapeutics, Inc. (Nasdaq: SRNE, “Sorrento”), today announced continuous sales growth in ZTlido® from quarter to quarter in 2020. Scilex expects third quarter 2020 ZTlido® net sales to grow 26% to approximately $7.2MM, compared to $5.7MM in Q2-2020. The preliminary third quarter 2020 net sales information presented in […] Read More »

October 1, 2019

Scilex Announces New Medicaid Agreements with CA & FL

PALO ALTO, Calif., Oct. 01, 2019 (GLOBE NEWSWIRE) — Scilex Holding Company (Scilex), a majority-owned subsidiary of Sorrento Therapeutics, Inc. (Nasdaq: SRNE), is excited to announce that its subsidiary, Scilex Pharmaceuticals, Inc., (together, with Scilex Holding Company, “Scilex”) has entered into multiple Medicaid agreements to facilitate access to ZTlido® (lidocaine topical system) 1.8% for nearly 6 […] Read More »

September 30, 2019

Scilex Holding Company Strengthens Board of Directors with Appointment of Two Highly Accomplished Pharmaceutical and Biotechnology Executives, Scott Whitcup, M.D. and Elizabeth Czerepak

PALO ALTO, Calif., Sept. 30, 2019 (GLOBE NEWSWIRE) — Scilex Holding Company (Scilex) today announced that it appointed Scott M. Whitcup, M.D. as lead independent director to its Board of Directors in May of this year. Dr. Whitcup is founder and Chief Executive Officer of Akrivista, LLC and Whitecap Biosciences, LLC, two companies focused on […] Read More »

September 23, 2019

Scilex Holding Announces Confidential Submission of Draft Registration Statement for Proposed Initial Public Offering

SAN DIEGO, Sept. 23, 2019 (GLOBE NEWSWIRE) — Scilex Holding Company (Scilex), a majority-owned subsidiary of Sorrento Therapeutics, Inc. (Nasdaq: SRNE), announced that it has confidentially submitted a draft registration statement on Form S-1 to the U.S. Securities and Exchange Commission (the “SEC”) relating to its proposed initial public offering of its common stock. The […] Read More »

April 15, 2019

Scilex Semnur Corporate Presentation

DOWNLOAD PRESENTATION Read More »

March 27, 2019

Scilex Holding, a Subsidiary of Sorrento Therapeutics, Announces Phase 2 Trial Results for its Leading SP-102 Program

Complete Enrollment of Phase 2 Trial to Characterize the Pharmacodynamics and Safety of Repeat Dose SP-102 Administered by Epidural Injection in Subjects with Lumbosacral Radiculopathy, a.k.a. sciatica All subjects experienced rapid reduction of leg and back pain following two SP-102 injection treatments, with group median for average pain in affected leg reduced over 50% throughout […] Read More »

March 22, 2019

Sorrento Therapeutics Announces the Merger of Scilex and Semnur to Create a Global Leader in Non-Opioid Pain Management

Semnur’s SP102, addressing multi-billion dollar unmet market needs, in Pivotal Phase 3 Trial with Fast Track Status from the FDA With non-opioid ZTlido, RTX, and SP102 commercial and near-commercial product lines, Sorrento and its subsidiaries are addressing $63 billion market in pain management (1) PDF Version SAN DIEGO, March 22, 2019 (GLOBE NEWSWIRE) — Sorrento […] Read More »

January 14, 2019

Scilex Announces Addition of ZTlido® to Express Scripts National Formularies

SAN DIEGO, Jan. 14, 2019 (GLOBE NEWSWIRE) — Scilex Pharmaceuticals Inc. (SCILEX), a subsidiary of Sorrento Therapeutics, Inc. (NASDAQ: SRNE), today announced that Express Scripts has added ZTlido® (lidocaine topical system) 1.8% to its commercial national formularies representing nearly 30 million lives.  ZTLIDO is indicated for relief of pain associated with postherpetic neuralgia (PHN), also […] Read More »

January 14, 2019

Scilex Announces ZTlido® Insurance Coverage for ~100 Million Insured Lives(1)

SAN DIEGO, Jan. 14, 2019 (GLOBE NEWSWIRE) — Scilex Pharmaceuticals Inc. (SCILEX), a subsidiary of Sorrento Therapeutics, Inc. (NASDAQ: SRNE), today announced that ZTlido® (lidocaine topical system) 1.8% (ZTLIDO) is covered by nearly 100M U.S. insured lives1.  ZTLIDO is indicated for relief of pain associated with postherpetic neuralgia (PHN), also referred to as post-shingles pain. […] Read More »

September 20, 2018

Scilex Announces Pricing and Availability of ZTlido™ for the Commercial Launch of its First Product in October of 2018

SAN DIEGO, September 19, 2018 – Scilex Pharmaceuticals Inc. (Scilex), a subsidiary of Sorrento Therapeutics, Inc. (NASDAQ: SRNE) (Sorrento), today announced that the Wholesale Acquisition Cost (WAC) for ZTlido™ (lidocaine topical system) 1.8% (ZTLIDO) is $8.98 per patch and is now listed in pricing compendia. Scilex expects commercial availability of ZTlido through wholesale distribution in […] Read More »

September 7, 2018

Scilex Presents ZTlido™ Data on Superior Adhesion over Lidocaine Patch Formulation

Data Presented at PAINWeek® Also Showed ZTlido Was Well-Tolerated and Demonstrated Bioequivalence to Lidoderm® Patch1,2 Study Results Make Strong Case for ZTlido as Non-Opioid Treatment for Post-Shingles Pain SAN DIEGO, September 7, 2018 – Scilex Pharmaceuticals Inc. (Scilex), a subsidiary of Sorrento Therapeutics, Inc. (NASDAQ: SRNE) (Sorrento), today announced data showing ZTlido™ (lidocaine topical system) […] Read More »

February 28, 2018

Sorrento Therapeutics Subsidiary, Scilex, Receives US FDA Approval for Non-Opioid ZTlido™ (lidocaine topical system) 1.8% for PHN Pain

SAN DIEGO, Feb. 28, 2018 (GLOBE NEWSWIRE) — Sorrento Therapeutics, Inc. (NASDAQ: SRNE) (“Sorrento”), and its majority-owned subsidiary, Scilex Pharmaceuticals Inc. (“Scilex”), received approval from the U.S. Food and Drug Administration (FDA) for ZTlido™ (lidocaine topical system) 1.8%. ZTlido is indicated for the relief of pain associated with post-herpetic neuralgia (PHN), also referred to as […] Read More »

November 14, 2017

SCILEX PHARMACEUTICALS, SORRENTO THERAPEUTICS’ SUBSIDIARY, FILES MARKETING AUTHORIZATION APPLICATION IN THE EUROPEAN UNION FOR ZTLIDO™

SAN DIEGO, November 14th, 2017 /GlobalNewswire/ — Sorrento Therapeutics, Inc. (NASDAQ: SRNE) (“Sorrento”), announced today that Scilex Pharmaceuticals Inc. (“Scilex”), a majority-owned subsidiary of Sorrento, filed the European Marketing Authorization Application (MAA) for its lead product candidate, ZTlido™ (lidocaine medicated plaster 1.8%), through a hybrid regulatory pathway with the Medicines and Healthcare products Regulatory Agency […] Read More »

September 12, 2017

FDA Acknowledges Receipt Of Sorrento Therapeutics Inc, NDA For ZTlido™; PDUFA Date Set For February 28, 2018

SAN DIEGO, Sept. 12, 2017 /PRNewswire/ — Sorrento Therapeutics, Inc. (NASDAQ: SRNE, “Sorrento”), announced today that SCILEX Pharmaceuticals Inc. (“SCILEX”), a majority-owned subsidiary of Sorrento, has received from the U.S. Food and Drug Administration (“FDA”) acknowledgement of receipt of its recently resubmitted New Drug Application (“NDA”) for ZTlido™ (lidocaine patch 1.8%) which has been considered a […] Read More »

August 31, 2017

Sorrento Therapeutics’ Pain Subsidiary, SCILEX Pharmaceuticals, Announces Positive Data from Head to Head Adhesion Study with its Lead Product, ZTlido™

– ZTlido™ demonstrated superior adhesion as compared to the reference product in the EU SAN DIEGO, June 14, 2017 /PRNewswire/ — SCILEX Pharmaceuticals Inc. (“SCILEX”), a subsidiary of Sorrento Therapeutics, Inc. (NASDAQ: SRNE, “Sorrento”) today announced that its lead investigational product, ZTlido™ (lidocaine medicated plaster 1.8%), has demonstrated superior adhesion versus the EU reference product Versatis® […] Read More »

August 30, 2017

Sorrento Therapeutics, Inc. Submits NDA For ZTlido™ Next-Generation Lidocaine Patch

SAN DIEGO, Aug. 29, 2017 /PRNewswire/ — Sorrento Therapeutics, Inc. (NASDAQ: SRNE) (“Sorrento”), announced today that SCILEX Pharmaceuticals Inc. (“SCILEX”), a majority-owned subsidiary of Sorrento, resubmitted the NDA and responded to all of FDA comments related to the initial NDA submission for its lead product candidate, ZTlido™ (lidocaine patch 1.8%).  ZTlido is a next-generation non-opioid, […] Read More »

January 9, 2017

Sorrento Subsidiary, SCILEX Pharmaceuticals, Announces Key Endpoints Met in the European Union Pivotal Bioequivalence Clinical Study for Its Lead Product, ZTlido™

– Marketing Authorization Application is expected to be filed in mid-2017 NEWS PROVIDED BY Sorrento Therapeutics, Inc. Jan 09, 2017, 09:00 ET SAN DIEGO, Jan. 9, 2017 /PRNewswire/ — SCILEX Pharmaceuticals Inc. (“SCILEX”), a subsidiary of Sorrento Therapeutics, Inc. (NASDAQ: SRNE, “Sorrento”) today announced that its pivotal study for its lead investigational product, ZTlido™ (lidocaine patch […] Read More »

December 5, 2016

Sorrento Subsidiary, SCILEX Pharmaceuticals Announces Key Endpoints Met in Pivotal Bioequivalence Clinical Study for Its Lead Product, ZTlido™

– 505(b)(2) NDA resubmission is expected in mid-2017 December 5, 2016 SAN DIEGO, Dec. 5, 2016 /PRNewswire/ — SCILEX Pharmaceuticals Inc. (“SCILEX”), a subsidiary of Sorrento Therapeutics, Inc. (NASDAQ: SRNE, “Sorrento”) today announced that its pivotal study for lead investigational product, ZTlido™ (lidocaine patch 1.8%), has met a primary endpoint establishing comparative pharmacokinetics and a secondary […] Read More »

November 8, 2016

Sorrento Therapeutics Closes Acquisition of Scilex

November 8, 2016 SAN DIEGO, Nov. 8, 2016 /PRNewswire/ — Sorrento Therapeutics, Inc. (NASDAQ: SRNE; “Sorrento”) and Scilex Pharmaceuticals Inc. (“SCILEX”) announced today the closing of a transaction by which Sorrento acquired a majority of SCILEX.  Sorrento acquired approximately 72% of the outstanding common stock of SCILEX for a net purchase price of up to approximately […] Read More »

April 22, 2016

SCILEX Pharmaceuticals Reports First-Line Treatments Including Lidocaine Patches for Post-Herpetic Neuralgia Are Significantly Underutilized

MALVERN, Pa.–(BUSINESS WIRE)–SCILEX Pharmaceuticals, Inc., a company engaged in the development and commercialization of products focused on the treatment of pain, reported data on how healthcare providers are currently treating patients with post-herpetic neuralgia (PHN) and how their prescribing choices compare with recommended guidelines. The data were presented in two studies at the AMCP Managed […] Read More »

February 23, 2016

SCILEX Pharmaceuticals Announces Senior Industry Hires

Malvern, PA, February 23, 2016 – SCILEX Pharmaceuticals, Inc., a company engaged in the development and commercialization of products focused on the treatment of pain, today announced the appointment of medical and regulatory affairs executives, as the Company advances in its assessment of several unique drug candidates. ZTlido™ (lidocaine patch 1.8%) is the Company’s first […] Read More »

December 10, 2015

SCILEX Pharmaceuticals Announces Executive Hires – Expanding team supports the ramp up of pain product suite

MALVERN, Pa., Dec. 10, 2015 /PRNewswire/ — SCILEX Pharmaceuticals, Inc., a company engaged in the development and commercialization of products focused on the treatment of pain, today announced the appointment of senior executives as it builds its team to support the commercialization of ZTlido™. ZTlido™ (lidocaine patch 1.8%) is a next-generation patch being developed for […] Read More »

September 17, 2015

FDA Accepts SCILEX Pharmaceuticals’ NDA Filing for ZTlido™

Malvern, PA, September 16, 2015 – SCILEX Pharmaceuticals, Inc., a company engaged in the development and commercialization of products focused on the treatment of pain, today announced that the FDA has accepted for filing its new drug application for ZTlido™ (lidocaine patch 1.8%). This marks a significant step on the path to commercialization for ZTlido™, […] Read More »

June 9, 2015

SCILEX Pharmaceuticals Announces Appointments of Internationally Recognized Industry Experts

Dr. Sanjay Gupta, President of the American Pain Association and a renowned physician with pain management expertise Dr. Philip Gerbino, an award-winning global pharmaceutical consultant and industry expert on market access MALVERN, Pa., June 8, 2015 /PRNewswire/ — SCILEX Pharmaceuticals, Inc., a company engaged in the development and commercialization of products focused on the treatment […] Read More »

April 6, 2015

SCILEX PHARMACEUTICALS ANNOUNCES STRATEGIC INVESTMENT BY ITOCHU CHEMICAL FRONTIER CORPORATION

SCILEX PHARMACEUTICALS ANNOUNCES STRATEGIC INVESMENT BY ITOCHU CHEMICAL FRONTIER CORPORATION Malvern, PA – March 19, 2015 – SCILEX Pharmaceuticals, Inc., a company engaged in the development and commercialization of products focused on the treatment of pain, today announced that ITOCHU CHEMICAL FRONTIER Corporation (ICF, Tokyo Japan), a member of ITOCHU Corporation (ITOCHU, 8001: TYO, ITOCY: OTC), one […] Read More »

September 11, 2014

SCILEX TO PRESENT AT AEGIS CAPITAL HEALTHCARE & TECHNOLOGY CONFERENCE

SCILEX TO PRESENT AT AEGIS CAPITAL HEALTHCARE & TECHNOLOGY CONFERENCE   MALVERN, PA. September 10, 2014 /PRNewswire/ — SCILEX Pharmaceuticals Inc., a company engaged in the development and commercialization of products focused on the treatment of pain, today announced that it will participate in the upcoming Aegis Capital 2014 Healthcare & Technology Conference to be […] Read More »

August 11, 2014

SCILEX Pharmaceuticals Featured In Philadelphia Business Journal

Please click the link below to read the complete article. http://www.bizjournals.com/philadelphia/blog/health-care/2014/08/pain-drug-developer-reels-in-5.html Read More »

May 5, 2014

SCILEX Pharmaceuticals Appoints Accounting And Finance Veteran Jerrold Sendrow To Board Of Directors

Mr. Sendrow Joins Pharmaceuticals Product Development and Regulatory Expert Eric Floyd, Ph.D. on the Board Malvern, PA – SCILEX Pharmaceuticals, Inc., a company engaged in the development and commercialization of products focused on the treatment of pain, today announced the appointment of finance and accounting veteran Jerrold Sendrow to the Company’s board of directors. Mr. Sendrow brings […] Read More »

March 24, 2014

SCILEX Pharmaceuticals Announces Filing of Investigational New Drug Application for Ztlido™

Pivotal pharmacokinetic bridging clinical study anticipated to begin in May. Malvern, PA – SCILEX Pharmaceuticals, Inc., a company engaged in the development and commercialization of products for the treatment of pain, today announced that it has filed an Investigational New Drug Application (IND) with the U.S. Food and Drug Administration for its first product Ztlido™ […] Read More »

March 21, 2014

SCILEX Pharmaceuticals Announces Completion of $5,000,000 Private Placement

Funds to be used for the clinical development of the Company’s first product Ztlido™ (lidocaine patch 1.8%) Malvern, PA – SCILEX Pharmaceuticals, Inc., today announced that the company has entered into definitive agreements for a private placement of common stock and warrants. The gross proceeds of the placement are expected to be approximately $5,000,000, before […] Read More »